Hepatic Sinusoidal Obstruction Syndrome in the Era of Defibrotide
نویسندگان
چکیده
منابع مشابه
Severe Hepatic Sinusoidal Obstruction Syndrome in a Child Receiving Vincristine, Actinomycin-D, and Cyclophosphamide for Rhabdomyosarcoma: Successful Treatment with Defibrotide
Hepatic sinusoidal obstruction syndrome (SOS) is a life-threatening syndrome that generally occurs as a complication after hematopoietic stem cell transplantation or, less commonly, after conventional chemotherapy. Regarding SOS in rhabdomyosarcoma patients who received conventional chemotherapy, the doses of chemotherapeutic agents are associated with the development of SOS. Several cases of S...
متن کاملSuccessful treatment with defibrotide for sinusoidal obstruction syndrome after hematopoietic stem cell transplantation.
Sinusoidal obstruction syndrome (SOS) (formerly known as hepatic veno-occlusive disease (VOD)) is a life-threatening complication subsequent to hematopoietic stem cell transplantation. However, no completely satisfactory strategies for the treatment of SOS have been established yet. Defibrotide is a single-stranded polydeoxyribonucleotide with anti-thrombotic, anti-ischemic, anti-inflammatory a...
متن کاملHepatic sinusoidal obstruction syndrome following hematopoietic stem cell transplantation.
J.m., a 43-year-old man with acute myelogenous leukemia with a monosomy 7 cytogenetic abnormality, received an allogeneic hematopoietic stem cell transplantation (HscT) from his human leukocyte antigen– matched brother. Past treatments included idarubicin and cytarabine induction therapy followed by a cycle of high-dose cytarabine. J.m. was in complete remission prior to the HscT. The condition...
متن کاملBiomarkers for hepatic sinusoidal obstruction syndrome after hematopoietic cell transplantation
which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Hepatic sinusoidal obstruction syndrome (SOS), previously known as veno-occlusive disease, is one of the major complications during the early period after hematopoietic cell transplantation (HCT). The disease is caused by toxic injury of conditioning therapy...
متن کاملManifestations and management of veno-occlusive disease/sinusoidal obstruction syndrome in the era of contemporary therapies.
The concept of veno-occlusive disease (VOD), along with our understanding of it, has historically been and remains an evolving phenomenon. This review presents a broad view of VOD, also known as sinusoidal obstruction syndrome (SOS), including (1) traditional hematopoietic stem cell transplant-associated VOD/SOS, (2) late-onset VOD/SOS, (3) pulmonary VOD, and (4) VOD/SOS associated with chemoth...
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ژورنال
عنوان ژورنال: Annals of Hematology & Oncology
سال: 2017
ISSN: 2375-7965
DOI: 10.26420/annhematoloncol.2017.1131